Read about MASALA in the Chicago Tribune

Read about MASALA in the Chicago Tribune

South Asians make up 60 percent of heart disease patients: ‘Everyone knows somebody who has had a heart attack’

Kate Thayer

Chicago Tribune |

Nov 26, 2019 | 8:00 AM

Munaf Patel, 43, puts on his gym shoes before walking the roughly 1.5-mile loop path outside of his office in Glenview on Nov. 21, 2019. After surviving two heart attacks beginning at age 39, Patel now walks regularly during his lunch hour, takes part in other athletic activities and has made dietary changes to improve his health. (Heather Eidson/for the Chicago Tribune)

Munaf Patel is an active husband and father. He plays cricket, basketball and volleyball, and runs around with his young kids in the family’s yard near the city’s Far Northwest Side.

So when he had an “uneasy” feeling in his chest in September 2015, he took some aspirin and followed up with his doctor. He was concerned but didn’t expect to hear what test results showed — at age 39, Patel was having a heart attack.

Despite the placement of a stent to unblock his artery, a quick recovery and watching what he ate, Patel had his second heart attack just eight months later.

“I was very active, and you don’t think about it when you’re young,” he said. “At the age that I am at, you don’t expect those things.”

But a part of him knew to be vigilant about his health; Patel, who is Indian, has an extensive family history of heart disease that many South Asians share. His family represents the heightened risk carried by South Asians, who experts say are about four times more at risk for cardiovascular disease — the leading cause of death in the U.S. — than other groups, and are stricken at younger ages.

As a young boy, Patel lost his father, who died in his 40s after a heart attack. Several other close relatives have had heart attacks at young ages, and one needed a heart transplant.

Munaf Patel, 43, checks his phone while walking the roughly 1.5-mile loop path outside of his office in Glenview on Nov. 21, 2019. After surviving two heart attacks beginning at age 39, Patel now walks regularly during his lunch hour, takes part in other athletic activities and has made dietary changes to improve his health. He also often turns on an app on his phone to track his steps during his walk. (Heather Eidson/for the Chicago Tribune)

Researchers continue to probe why it seems that, in the South Asian community, everyone knows someone who has had a heart attack. Experts say that while the group represents about a quarter of the world’s population, it accounts for about 60% of heart disease patients.

The alarming risk has prompted researchers to study South Asians in the long-term Mediators of Atherosclerosis in South Asians Living in America study, known as Masala (meaning spice blend), in part because medical guidelines physicians historically use come from data derived from white men. Yet South Asians, researchers say, often do not show some of the typical signs of cardiovascular disease and need their own guidelines. Experts also say it’s important to distinguish South Asians — those from India, Pakistan, Sri Lanka and other countries in the region — from other Asian groups because their risks differ.

This work has led to a shift in recommendations last year from the American Heart Association and other medical organizations, directing physicians to consider ethnicity when assessing patients’ cardiac health. The move recognized that South Asian patients tend to carry lower levels of good cholesterol in their blood, among other health distinctions.

There’s also an effort to educate South Asians about the risk they carry that might be surprising or go unnoticed, but possibly could be offset by diet and exercise. At Advocate Lutheran General Hospital’s South Asian Cardiovascular Center, clinicians have amped up their efforts with a video series that provides heart healthy recipes and encourages sound lifestyle choices.

Dr. Shoeb Sitafalwalla, a cardiologist and medical director of the center, works with a team that treats South Asian patients and also goes into the community, spreading the word that healthy eating and exercise could help offset their genetic predisposition. That includes regular visits to speak at churches, mosques, restaurants and grocery stores that sell ingredients used in South Asian recipes.

Dietitian Srisakthi Ramanathan helps shopper Leena Joshi, from Roselle, with a healthy diet plan at Patel Brothers Grocery Store on Nov. 21, 2019, in Schaumburg. South Asians are about four times more likely to have heart disease, and it affects them earlier. As researchers continue to look into exactly why, a team at Lutheran General hospital that works to educate South Asians about their risk, heart healthy eating and lifestyle had developed a series of videos. Some offer recipes, and some work to dispel myths and encourage good health practices. (John Konstantaras/for the Chicago Tribune)

To expand its audience, the group created a video series, called “Dil Se,” a Hindi phrase that means “from the heart.” The first seven in the 25-video series launched over the past few months.

Sitafalwalla said that while South Asians likely have heard of this risk because of knowing others affected, it’s not talked about enough.

“You talk about how your daughter got into law school,” he said. “You don’t talk about how your son just had a heart attack.”

The advocacy work of the cardiovascular center “started as a grass-roots operation, going into communities ... taking our message of health and wellness,” he added. “But we were limited in scale. There are 300,000 South Asians living in Illinois. We needed to find a way that could help us bring that message to a greater amount of people.”

The team came up with the video series concept as a way to “interact with the community, especially where their eyes are most — their mobile phones,” Sitafalwalla said. A grant from Boehringer Ingelheim Pharmaceuticals helped fund the project.

Some of the videos resemble rapid-fire cooking videos popular on social media, and include facts on wise food choices for those concerned about cholesterol or blood sugar. South Asians are also at a greater risk for diabetes, Sitafalwalla said.

Others tackle myths or home remedies Sitafalwalla said are common within South Asian communities, from drinking apple cider vinegar to unblock arteries to rubbing lemons on skin to get rid of dark spots on the skin — a sign of diabetes.

Dietitian Srisakthi Ramanathan said the video recipes for healthier versions of South Asian cuisine include a mock-up of a nutrition label for the dish. “That’s hard to find in Indian recipes. That’s a big gift.”

During community demonstrations, Ramanathan said, she’ll hear from South Asians that it’s eye-opening to learn about the nutritional makeup of certain foods, as well as portion control, especially with oil.

Dietitian Srisakthi Ramanathan helps shoppers with healthy diet plans at Patel Brothers Grocery Store on Nov. 21, 2019, in Schaumburg. (John Konstantaras / Chicago Tribune)

South Asians have a cultural connection with oil, she said, as well as a desire not to waste it. “Even now, my mom will hide the oil because they don’t want us to find it and throw it away.”

“When you’re entertaining or serving your family, adding more oil is considered a sign of generosity,” added Sitafalwalla. “So when the pot of curry sits down on the table, if there isn’t an oil slick you can see, it’s not generous. What you don’t realize is you’re also being really generous in how you’ll clog up their arteries.”

But educating the community doesn’t mean wiping away traditions, he said, and the team tries to be culturally sensitive. “All of the choices that we lay out … are pragmatic ones. We’re under no illusion that people are going to give up staple items that are culturally ingrained.”

Given the inherited risk, eating right and exercising are especially important for South Asians, Sitafalwalla said, and it’s important to learn from a young age, noting that 25% of heart attacks among South Asians occur before age 40, and half occur before 50.

Dr. Namratha Kandula, a Northwestern University researcher involved in the ongoing, long-range Masala study, said it’s vital to better understand why the group has these risks “because they don’t fit the typical pattern of someone at risk of heart attack and stroke.”

South Asians are typically not overweight and do not use much tobacco, common risk factors for heart disease.

But through the ongoing study, researchers have learned the group has other risk factors, like high blood pressure, less lean muscle mass and a tendency to store fat in the liver and abdomen.

Kandula said there are also cultural differences, like not regularly exercising. Yet “exercise is very important because of the South Asian body type,” she said.

“The goal isn’t really to lose weight,” but to build lean muscle, she said.

Kandula promotes this and other healthy concepts in another study she’s leading: the South Asian Healthy Lifestyle Initiative, or Saheli (meaning friend), which helps participants change behaviors by incorporating exercise and healthy foods into their lives. The 16-week program, in its third year, works with community partners and so far has recruited more than 300 South Asian participants in the area. The goal is to reach about 550 in the next couple of years, Kandula said.

While members of the South Asian community are aware of these risks, they might be reluctant to discuss and seek guidance, Kandula said.

“Everyone knows somebody who has had a heart attack at a young age. It’s very common,” she said. “But how do you get support to help manage them? It’s sort of your own problem.”

Saheli study participant Ravi Natarajan, 48, of Naperville, enrolled in the study last fall after hearing about it at his temple. While Natarajan said he’s “pretty healthy,” his father had a heart attack at 68, and he also has had friends in their 30s experience heart attacks.

“I wanted to learn more about prevention,” he said.

Through the study, he learned to keep food logs, received regular cholesterol and blood sugar checks, and talked about ways to manage stress. Natarajan said he now incorporates more fruit and healthy grains into his diet, and added strength training to his walking and running routine.

The result is lower cholesterol and he shed a few pounds, but Natarajan said he also has benefited from awareness of his risks, now leading a healthy life and setting an example for his sons.

“My sons are watching me,” he said. “We cannot control ... some of the family history. What we can control is the exercise as well as the food habits.”

Patel, now 43, said he’s doing well and is fully recovered from his two heart attacks. He said he remains active and only indulges in fried shrimp and some of his other less nutritious favorites every once in a while.

He also tries to talk to others in his community about their shared risks, especially those hesitant to pay attention to markers like high blood pressure, or those who don’t get regular doctor checkups.

“It can happen to anyone; it doesn’t matter how old,” Patel said. “You get worried about your family, your kids, yourself.”

What have we learned about how Religion/Spirituality may affect Health in the MASALA Study?

What have we learned about how Religion/Spirituality may affect Health in the MASALA Study?

By Blake Victor Kent, PhD

 A lot of research has looked at the relationship between religion and health. Researchers have been interested not only in religious activities like frequency of attending religious services, praying, and meditating, but also in things such as yoga practice, feelings of closeness to God or the divine, and whether people’s interactions with others who practice their religion are positive or negative. Broadly speaking, researchers have investigated not just “religion” per se, but also “spirituality.” Questions related to religion tend to focus more on organizational aspects, while questions on spirituality tend to be about personal experiences outside the confines of institutional religion.

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Thousands of studies have been conducted on religion/spirituality and health, and what constitutes “health” has ranged anywhere from depression to hypertension to cancer to mortality. Most of this research has been conducted in the U.S., typically on samples that are predominantly white and Christian. These studies have often found positive relationships between religion/spirituality and health or no relationship at all. However, in some cases, religion and spirituality have been linked with negative outcomes. Researchers have been able to demonstrate that when the relationship is positive it is often because religion and spirituality provide ways of coping with problems, and when it is negative it is often because of negative perceptions of the divine or negative experiences with others in their religion.

Prior to MASALA there were only two studies examining religion/spirituality and health among U.S. South Asians. Our team of researchers, in cooperation with scholars at Harvard Medical School, published three new papers looking at the associations between religion/spirituality and health in the MASALA study. These studies provide an important foundation for future work in the South Asian population.

The first study focused on religious group involvement, and looked at religious affiliation, religious attendance, participation in group prayer outside of religious services, giving and receiving love and support to and from fellow congregants, experiencing neglect by fellow congregants, and being criticized by fellow congregants. The second study examined private religious and spiritual practices and beliefs, which included frequency of prayer, yoga practice, belief in God/the divine, gratitude, non-theistic daily spiritual experiences (i.e., connections with the transcendent not specific to a religion or god), theistic daily spiritual experiences, feelings of closeness to God/the divine, positive religious coping (i.e., God/the divine provides comfort and support during times of stress), negative religious coping (i.e., feeling punished by God/the divine when things go wrong), religious and spiritual struggles (i.e., stress causes doubt about religious beliefs), and feelings of hope in God/the divine. The third short study looked at one variable: the degree to which people consider themselves to be religious or spiritual.

We examined four different health outcomes for each study: self-rated health (“rate your overall health on a scale of 1-5”), mental health (i.e., depressive symptoms), feelings of anxiety, and feelings of anger.

What did we find? First, for group religion, we found that Jains reported better self-rated health than Hindus and Muslims. Group prayer outside of religious services was associated with better self-rated health and mental health, along with lower anxiety and anger (these were strongest for regular participants). Giving and receiving love and care in the congregation was linked to better self-rated and mental health, along with lower anxiety. Congregational criticism was associated with higher anxiety and anger. Finally, religious service attendance was associated with higher levels of anxiety. Many of these results follow the patterns identified in other studies, largely indicating that participating in group religious practices is related to good health. Congregations provide places for friendship, acceptance, reinforcement of cultural norms and beliefs, and experiences of the transcendent. They also provide relationships that can lead to practical forms of material support, such as financial assistance in hard times or rides to the doctor.

One finding, however, was different than much of the existing literature: here, religious attendance was associated with increased anxiety rather than less anxiety. We suspect this could have something to do with something called “resource mobilization.” In short, when people experience distress they turn to religious sources of support to find help. This means it is possible that increased anxiety might lead to increased religious attendance (rather than the other way around). It is important to note that this finding could emerge since the largest group in the sample – Hindus – tended to report lower levels of attendance (which is expected given differences in organization and practice for this group). About 23% of Hindus attended religious services weekly or more, compared to 66% of Muslims. Evangelicals and Catholics examined in other studies had similar rates of attendance as Muslims. This reinforces the explanation that those who attend services less often sometimes turn to religious resources for support in times of distress.

The second study, which focused on individual (or private) religious and spiritual practices, had a number of interesting findings: yoga, gratitude, non-theistic spiritual experiences, closeness to God, and positive coping were associated with better self-rated health. Gratitude, non-theistic and theistic spiritual experiences, closeness to God, and positive coping were associated with better mental health; negative coping was associated with poorer mental health. Gratitude and non-theistic spiritual experiences were associated with less anxiety; negative coping and religious/spiritual struggles were associated with greater anxiety. Non-theistic spiritual experiences and gratitude were associated with less anger; negative coping and religious/spiritual struggles were associated with greater anger.

The most consistent of these variables was non-theistic daily spiritual experiences, which was beneficially associated with all four of the outcomes. This measure assesses the degree to which the individual lives in the moment and makes spiritual connections between themselves and the world around them. For example, one item states, “I experience a connection to all of life,” and another reads “I am touched by the beauty of creation.” Such “in-the-moment” presence appears strongly related to well-being, regardless of one’s religious affiliation, and we have found that the measure may be especially suited for examining Dharmic faiths (i.e., Hinduism, Jainism, Sikhism, and Buddhism). Many of the other results reflect positive associations for gratitude, yoga practice, and closeness to God/the divine, but negative associations for negative religious coping and religious/spiritual struggles.

Lastly, the third study examined how religious or spiritual people considered themselves to be. Interestingly, we found that being both “very” religious/spiritual or “not at all” religious/spiritual were associated with lower levels of anxiety and higher levels of self-rated health, whereas those identifying as “slightly” or “moderate” religious/spiritual reported higher levels of anxiety and lower levels of self-rated health. This pattern has been seen in a small number of studies of religion/spirituality and health.. Those who are very secure in their faith or those who have no faith at all often appear very similar in terms of health. It is those who are uncertain of their faith, however, those who are “somewhere in the middle” that tend to report worse health. This makes a good deal of sense, since experiences of doubt or frustration in one’s faith are likely to be associated with various forms of ill health, particularly poorer mental health. Of course, in most cases people don’t choose to believe or not believe in their faith for the sake of mental health, but this information provides some insight for religious adherents to examine themselves, their beliefs, and their practices, perhaps in conversation with family members or trusted spiritual advisers.

In summary, religious and spiritual beliefs and practices in the MASALA study appear to be associated with better health. However, these data are preliminary! The riches of the MASALA study will provide many more opportunities in the future to examine religion and spirituality, along with a host of other mental and physical health outcomes.  

Read about MASALA featured in India Abroad

Why South Asians are at a greater risk of heart disease than other ethnic groups

Why South Asians are at a greater risk of heart disease than other ethnic groups

By Suman Guha Mozumder

Feb 26, 2019 (PDF Link)

 

On a flight home from Mexico a couple of years ago, Silicon Valley-based academic and entrepreneur Vivek Wadhwa felt a shooting pain in his left arm.

 

Wadhwa, then 45, did not feel much concerned as he had never been sick in a decade, but on arrival when he went to the University of North Carolina Medical Center for a checkup, he learnt he suffered a heart attack and needed two stents in his arteries.

 

Fortunately for Wadhwa, the Indian-American Distinguished Fellow and professor at Carnegie Mellon University Engineering, Silicon Valley, the sudden pain passed without any serious incident.

 

Another IT professional from Southern India, identified by researchers by his first name Sundar, suffered a sudden chest pain and a heart attack a few years ago in Illinois, although the 42-year old vegetarian did not have the typical profile of a high-risk candidate for heart disease: he weighed about 150 pounds, had a Body Mass Index (BMI) of 25, earlier classified as a healthy weight in an individual, was a nonsmoker and did workouts regularly.

 

Sundar also survived the heart attack, but experts say incidents like the one experienced by people like Wadhwa and Sundar are not at all uncommon in the South Asian community in the U.S., where almost everyone knows somebody among their friends and relatives who have died of some cardiovascular disease or suffered a heart attack or a stroke.

 

Experts have known for years that South Asians have an increased chance of developing cardiovascular disease, but the problem is that in the absence of any scientific research focused exclusively on the community, it has remained somewhat of a mystery as to why South Asians have a higher burden of cardiovascular risk factors at younger ages.

 

According to experts, South Asians have a higher risk of myocardialinfarction and higher proportionate mortality from

cardiovascular disease compared with most other race/ethnic groups in the United States. These experts admit that although Indian-Americans do not usually fit the typical profile of someone vulnerable to heart attacks or other major heart-related ailments, they have an increased chance of developing cardiovascular diseases and suffer a higher death rate than any other ethnic group.

 

Traditionally, South Asians’ preference for oil-rich food with lots of refined carbohydrate and high sugar consumption have been blamed for many an illness, including diabetes and heart diseases, but experts say such food habits alone may not be adequate to explain the reason for high incidence of cardiovascular disease among South Asians.

 

The American Heart Association noted in 2018 that South Asians living in the U.S. are more likely to die from heart disease than the general population, but this risk, it said, has been largely hidden by a lack of data.

 

To understand this issue better and study the issue in greater depth as to why South Asians — people from India, Pakistan, Bangladesh, Sri Lanka, Nepal, Bhutan and the Maldives — are at a greater risk for heart disease than other ethnic groups, and why they are four times more vulnerable to cardiac disease than the general population, a group of researchers has embarked on a research study on the subject since 2010.

 

This long-term research study has received substantial funding from the National Institutes of Health and is led by Alka Kanaya of the University of California, San Francisco and Namratha Kandula of Northwestern University in Chicago, the two co-principal investigators of the first-of-its-kind study on heart disease among South Asians in the U.S.

 

The idea is to find out the reasons for the high prevalence of heart diseases among South Asians, and if there are risk factors that are different than those found in the general population. The goal of the study is to generate new knowledge to improve the prevention and treatment of heart disease in South Asians.

 

The research study which is known by its acronym MASALA (Mediators of Atherosclerosis in South Asians Living in America), is being conducted in a population-based sample of 1164 South Asian men and women aged 40–84 years at the two university clinical field centers in San Francisco and Chicago.

 

“This is really a puzzle — why south Asians have higher rates of heart diseases compared to other racial and ethnic groups — and that is exactly why we are doing this study because no one seems to have an answer to that puzzle,” Kanaya, Associate Professor of Medicine in the Division of General Internal Medicine at UCSF, who is the research study’s co-principal investigator along with Kandula, told India Abroad.

 

The importance of the study lies in the fact that heart disease is the number one cause of death worldwide and accounts for 30 percent of all deaths.

 

South Asians comprise 60 percent of the world’s heart disease patients. South Asians have the highest death rate from heart disease in the United States compared to other ethnic groups. Studies from around the world have also shown that South Asians have a higher burden of cardiovascular risk factors at younger ages.

 

According to American Heart Association, there are around 3.4 million people of South Asian descent living in the U.S. as of 2010, based on the U.S. Census Bureau data.

 

Despite their numbers, the threats to South Asians’ cardiovascular health have been obscured because researchers have been looking at Asian-Americans as a monolithic group. When examined individually, South Asians have a higher risk of heart disease than other Asian groups, especially East Asians from China, Japan and Korea, according to the American Heart Association.

 

Studies of Japanese, Latinos and other groups have usually found that adapting to a Western culture increases rates of diabetes, high blood pressure or other risk factors for heart disease.

 

But MASALA’s participants reveal a different trend. The process of acculturation may be different for South Asians.

 

In 2017 Congresswoman Pramila Jayapal (D-Wash.) announced the introduction of the South Asian Heart Health Awareness and Research Act. The bipartisan bill, co-sponsored by Rep. Joe Wilson (R-S.C.), sought to raise awareness of the alarming rate at which the South Asian community was developing heart disease and to invest in ways to reverse this trend.

 

It also sought to include a Sense of Congress that U.S. medical schools should include as part of their nutrition curriculum, a focus on South Asian diet and ways to achieve optimal nutrition in these populations.

 

The bill also sought to create South Asian Heart Health Promotion Grants at the Centers for Disease Control to develop a clearing house and web portal of information on South Asian heart health and to develop culturally appropriate materials to promote heart health in the community and provide grants to work with community groups involved in South Asian heart health promotion.

 

“I would say that we have some clues to the puzzle, but we haven’t completely solved the puzzle as yet, and one of the first clues is the fact that South Asians have a lot of fat inside the body around the abdominal area, in the liver and around the heart,” Kandula, the other principal investigator for the MASALA study, who is associate professor of Medicine (General Internal Medicine and Geriatrics) and Preventive Medicine, told India Abroad.

 

Both Kandula and Kanaya said that even though the South Asians have a low body mass index, they tend to accumulate a lot of fat in certain parts of the body like the abdominal area that causes different types of inflammation and activate certain biological pathways that contribute to Atherosclerosis or hardening of arteries. “I definitely think this is an important contribution of our MASALA study and extends what we know about heart disease,” Kandula said.

 

The MASALA study is modelled on the 2001 Multi-Ethnic Study of Atherosclerosis (MESA), involving more than 6,000 men and women from six communities in the United States, including Chinese, Latino, Black and White and it has also learned from the Framingham Heart Study, a long-term, ongoing cardiovascular cohort study on White males of Framingham, Massachusetts that started in 1948 with 5,209 adult subjects.

 

But MASALA researchers said that none of the earlier studies in the U.S. had focused on South Asians and therefore, there is very little data available about the unique cardiovascular issues relating to South Asians.

 

Thanks to new information based among others on MASALA research, the American College of Cardiology, American Heart Association and 10 other health organizations, have issued new guidelines in November last year, stressing how race and specific ethnic characteristics may influence a person’s risk of developing cardiovascular diseases.

 

The guidelines also made clear distinctions among different Asian ethnicities, noting that people of South Asian descent have “a higher risk” of developing heart disease than the general American population.

 

“Everybody’s looking for a simple explanation, like it’s the diet or because people don’t exercise, because people are too stressed out, but the higher risk for heart disease in South Asians is most likely the result of several different factors acting together,” Kandula said. “So, there may be the genetic predisposition that is exacerbated by certain environmental factors and that can be made worse by stress or poor diet. We are thinking about how different factors interact to cause disease, and not just a single variable explaining this problem,” she said.

 

Similarly, Kanaya said the researchers are looking at all different factors, including genetics and epigenetics, dietary and physical factors and things like discrimination, psychological stress and depression and anxiety. “You can say we have a holistic approach and are taking a lot of things into consideration to understand this puzzle,” Kanaya told this correspondent. “We are taking a deep dive into South Asians cardiovascular health,” Kanaya said.

 

But she and Kandula emphasized the need to continue the study and follow participants over time, which will require longterm commitment from participants and continued funding “It is a relatively young study, started 10 years ago, and we need to follow people for at least 10 more years to find more definitive answers about the true incidence of heart disease in the U.S. South Asian community,” Kanaya told this correspondent.

 

According to the MASALA researchers, the same group of cohorts, some 1164 South Asian men and women, most of them from India but also from Pakistan and other countries — come every couple of years to the two clinical research centers in San Francisco and Chicago where various medical tests and blood work are done on them to monitor their health.

 

To begin with, the cohorts have to be South Asians, living permanently in the U.S and having no heart condition, meaning they have not been diagnosed with heart problems or and undergone any cardiac procedure done on them.

 

“We follow these healthy, middle-aged South Asians and we monitor them to find out if they develop any heart related issues over time, and if they do, we try to understand why it could have happened.

 

“And if someone stays healthy, that is also useful information because we can try to understand what are the factors that keep South Asians healthy, and free of heart disease” Kanaya said. The participants come for five hours of testing that includes CT scans of the heart, the abdomen and ultrasound of the neck arteries as well as EKGs, followed by blood samples.

 

“We keep the blood samples since we also want to do genetic studies,” Kanaya said.

 

Besides the fact that both the principal investigators are interested in the science of South Asians cardiovascular diseases they also have personal reasons to be committed to heart heath care. “My grandfather died of heart attack in India at the age of 56, and I grew up with his story, and I have always wondered why my grandfather died at a young age,” Kandula said.

 

“This is why I am passionate about the issue, and as an immigrant, I am committed to improving healthcare in the U.S. for immigrant communities.”